Sweet Dicer

Sweet dicer: impairment of micro-RNA processing by diabetes.

Dicer-dependent small RNAs

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Dicer cuts the kidney.

We should occasionally stop, take a breath, and reflect about what is happening at the interface between medicine and science. Collectively, we are uncovering paradigms that are relevant to understanding disease at a frantic pace. One can only turn to wonder, in this moment of reflection, when trying to imagine what it must feel like as a treating physician trying to filter all of these new con...

The Sweet, Sweet Smell of Diacetyl

Chemosensation in C. elegans Worms have a very simple chemosensory system composed of 32 neurons. Despite this simplicity, they are capable of detecting and appropriately responding to a Dallas, Texas 75235-9111 wide range of chemicals (Bargmann et al. Lucretius, one of the early Greek atomists, suggested have shown that chemoattraction to a number of mole-that all substances having odor gave o...

Shaping chromatin with DICER

The accessibility of chromatin is an essential feature of DNA templated processes such as DNA replication, transcription and DNA repair. The chromatin condensation state, and thus accessibility, is modulated by a variety of chromatin remodeling complexes [1] as well as epigenetic components; for instance by bridging gene regulatory elements [2]. More recently, the function of ncRNAs in regulati...